Protein Info for GFF1544 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Transcriptional regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 transmembrane" amino acids 248 to 268 (21 residues), see Phobius details PF00356: LacI" amino acids 10 to 55 (46 residues), 52.5 bits, see alignment 6.7e-18 PF00532: Peripla_BP_1" amino acids 67 to 321 (255 residues), 67.3 bits, see alignment E=3.1e-22 PF13407: Peripla_BP_4" amino acids 71 to 316 (246 residues), 35.3 bits, see alignment E=1.9e-12 PF13377: Peripla_BP_3" amino acids 176 to 340 (165 residues), 122.2 bits, see alignment E=4.8e-39

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 36% identity to bja:blr6378)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>GFF1544 Transcriptional regulatory protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
VKETSPRKPTVSDVARHAGVSPGSVSRVLTGKNWVSDDLRKQVLEAARALNYIPNSVAQS
LKTQRTMTVGAIVSDMANPLHGRFLAAVQERLEAEGYFLIVANDKSQPERDVALLELFGR
GRVDGVIAGIADELHPRTLQALQSLRLPVVFHDRDLLGIGDAVGPDHRMGAHEATRHLIG
LGHRRIALMTPSASIRPGRERLAGYREALQEAGIEYDPALEAILEASGGDMAFSATKHML
GQAQRPTAVICLGTQMLAGVMSAVGTLGLSVPRELSLIGIGDTELVRLSTPAITAVRWDI
ALCGRWAAEMMLERLREDGEERAPYRMLEMPTEMVLRHSCAPPLAG