Protein Info for GFF1505 in Variovorax sp. SCN45

Annotation: Cytosolic acyl coenzyme A thioester hydrolase, inducible (EC 3.1.2.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 70% identity to bav:BAV1558)

Predicted SEED Role

"Cytosolic acyl coenzyme A thioester hydrolase, inducible (EC 3.1.2.2)" (EC 3.1.2.2)

MetaCyc Pathways

oleate biosynthesis II (animals and fungi) (2/2 steps found)
bacterial bioluminescence (5/8 steps found)
stearate biosynthesis I (animals) (2/6 steps found)
stearate biosynthesis III (fungi) (1/6 steps found)
sporopollenin precursors biosynthesis (8/18 steps found)
cutin biosynthesis (3/16 steps found)
suberin monomers biosynthesis (5/20 steps found)

KEGG Metabolic Maps

Biosynthesis of unsaturated fatty acids

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>GFF1505 Cytosolic acyl coenzyme A thioester hydrolase, inducible (EC 3.1.2.2) (Variovorax sp. SCN45)
MLSITPEDALIDVPRRIAVDGLAPGEQIEIASCTQRGRGVPWRASARFVADASGTVDLQR
DAPVAGSSYEGVSAMGLVWSQVPDTPGAREQFGAVPGAALRTDISVRRGGDAAELQGRFV
QRLAGEGVTRRDVREESLVGTLYLPAGPGPHPAVMILNGSGGGINEPRAALYASHGYAAF
ALAYFKAPGLSDYISNTRLEYFETALAWLHRTVRPAHGFVALSGQSRGGELVLLLGTLFP
ESVSAVIGYVPGAVVHCAQNACDPSLGREGPAWIFRGQPLPHVWENNRTATWAPWDEGPE
PRRHADALRTALQDPEAVERARIRVEQIRGPVMLLSATDDGSWPSSLYSRMVTERLAQFE
HPHAVEHLDFEGAGHSILFPYVPTTQLGYAHPVSGRRSTSGGTPANNAHADEASWQGVLR
FLQQAVAARTASSGDTTHD