Protein Info for PS417_07625 in Pseudomonas simiae WCS417

Annotation: helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 897 PF04434: SWIM" amino acids 74 to 97 (24 residues), 23.5 bits, see alignment (E = 6.3e-09) PF04851: ResIII" amino acids 425 to 580 (156 residues), 28.7 bits, see alignment E=2.3e-10 PF00176: SNF2-rel_dom" amino acids 429 to 708 (280 residues), 250.5 bits, see alignment E=3.9e-78 PF00271: Helicase_C" amino acids 724 to 833 (110 residues), 78.6 bits, see alignment E=8.3e-26

Best Hits

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU1563)

Predicted SEED Role

"COG0553: Superfamily II DNA/RNA helicases, SNF2 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZ94 at UniProt or InterPro

Protein Sequence (897 amino acids)

>PS417_07625 helicase (Pseudomonas simiae WCS417)
MPLTASLTKPLAPSWANRFKEQSLERGRRYALENRVRIVECGDSTIVASCEGSGGNVYRQ
TISLRESAKGTLILVDSRCTCPVHTNCKHIAAVLLKVQETLAYPAAAQDAELLEKLQAVL
ENRVAFPQVVMEDVVPVPRLWLASVEFSAFEPRNGKMQRYIQHRAALSFNYLGNYVSGQK
NADIIVRQETQSLRIKRHPELEQPYREQLRLLGFKIATRQSKALPESAGELFEMVNDSAW
LNFTLNASPTLRAEGWELQIDEDFGFDLSAVDDWYATVDEGPERDWFDLELGIIVNGERL
SLLPILLNLMRSHTEILNPEKLARRRDDELILVNIPGLPNGGHGPLQVALPYGRLKPVLA
TLGEFYLQDAGTTTLRLAKADAIRLNPLEDLPLQWEGGEKIRNFAQRLRDIKDFTCVAPE
GLNATLRPYQLEGLSWMQSLRQLEVGGILADDMGLGKTLQTLAHILTEKIAGRLDRPCMV
VMPTSLIPNWLDEAAHFTPQLNVLALYGAARKKHFATLQDYDLLLTTYALLPKDIEQLSA
LPLHVLILDEAQYIKNPSSKAAQAARELNARQRLCLSGTPLENHLGELWSLFHFLLPGWL
GDVKSFNRDYRTPIEKRASDVRLQHLNGRIKPFLLRRTKEQVATELPPKTEIIHWVDLNE
AQRDVYETMRLAMDKKVRDEITRKGVARSQIIILEALLKLRQVCCDLRLVNDATLPARGS
SSGKLDSLMEMLAELFEEGRRILLFSQFTSMLSLIEVELKKRGVAYALLTGQTRDRRTPV
KDFQSGKLQIFLISLKAGGVGLNLTEADTVIHYDPWWNPATENQATDRAYRIGQEKPVFV
YKMIARGTVEEKIQHLQKEKSDLAAGVLDGRTTGDWQLGNEDIEALFAPLPHKQEKR