Protein Info for GFF149 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 48 to 66 (19 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 176 to 194 (19 residues), see Phobius details amino acids 198 to 215 (18 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 307 to 327 (21 residues), see Phobius details amino acids 341 to 364 (24 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 45 to 400 (356 residues), 446.4 bits, see alignment E=3.7e-138 PF01098: FTSW_RODA_SPOVE" amino acids 47 to 402 (356 residues), 443.9 bits, see alignment E=2.1e-137

Best Hits

Swiss-Prot: 90% identical to FTSW_ECO57: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Escherichia coli O157:H7

KEGG orthology group: K03588, cell division protein FtsW (inferred from 100% identity to spt:SPA0129)

MetaCyc: 90% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>GFF149 Cell division protein FtsW (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MRLSLPRLRMPRVPGFGLLAWLFAALKGWVMASRDKDADSLIMYDRTLLWLTFGLAAIGF
VMVTSASMPVGQRLANDPFLFAKRDALYIFLAFCLAMVTLRLPMTFWQKYSTTMLIASII
MLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYLANYLVRKVDEVRNNLRGFLK
PMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
PYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEIWGQGLGNSVQKLEYLPEAHTDFIF
AIIGEELGYIGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNV
GAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMFLLRIDYETRLEKAQAFTRGSR