Protein Info for GFF1486 in Variovorax sp. SCN45

Annotation: Tetrapartite efflux system, inner membrane component FusBC-like

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 687 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 35 to 52 (18 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 85 to 103 (19 residues), see Phobius details amino acids 110 to 132 (23 residues), see Phobius details amino acids 145 to 170 (26 residues), see Phobius details amino acids 373 to 394 (22 residues), see Phobius details amino acids 400 to 417 (18 residues), see Phobius details amino acids 427 to 446 (20 residues), see Phobius details amino acids 452 to 470 (19 residues), see Phobius details amino acids 477 to 496 (20 residues), see Phobius details amino acids 508 to 528 (21 residues), see Phobius details PF04632: FUSC" amino acids 11 to 681 (671 residues), 557.3 bits, see alignment E=6.1e-171 PF13515: FUSC_2" amino acids 23 to 154 (132 residues), 46 bits, see alignment E=5.7e-16

Best Hits

KEGG orthology group: None (inferred from 59% identity to vpe:Varpa_0909)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (687 amino acids)

>GFF1486 Tetrapartite efflux system, inner membrane component FusBC-like (Variovorax sp. SCN45)
MKRTRFSRQEMLFSLKSFAGAMLALYVASRAGLPRPFWAFMTAYIVAHPLAGNVRSKALY
RFVGTLAGCAATVVLIPSLSASPELLSLALALWTGLCLYLSLLDRSARSYVFMLAGYSAA
LIGFPLVEAPAAMFDTAVARVQEIGLGILCASLVHSIALPAGLAPPLLGLMDRALGDARR
WMTDLLRDGLARTDGARMAADRQRLALDITQLRLLSTHVPFDTGNLRWTTGAVRAMQDRI
SALTPTLSAIEDRLEALKTAEGEVPRDIVSALERRSAWMAPQVPGSPDALPPTGEAMDEA
RAAFRALADGPASSPWVRALRIDLAVRLEELMVDWHACTVLRGDIDAGLAGAAPRPRSAA
ALGHKVLHLDRGLALRSALTAVLATCACCAIWILTAWPSGSAAAMSAAVFCSFFATMDDP
VPAMHKFVVALLWSLPASVFCVLAVMPLARDFGMLALCIAPFFLVVGCYIARPASSLAAL
GMFFGVAGTLALQDTASADLPSLVNSNLALILGGVAAARVTALVRSVGSDWSAKRIRRAT
WRDLAALAQRPQDASGRDAYAGRMLDRIAQLAPRTAPGKGEQAQADARRALRDLRIGADI
VALQQQRRGLPASAVDRLFDDLGRVFRAQAAGVPRRHESLLPRIDGLLLDTLPVDTARPS
IDTAGAIAALVGLRRNLFPAANGALQP