Protein Info for GFF1472 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Regulatory protein, LuxR:Response regulator receiver

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 PF00072: Response_reg" amino acids 4 to 116 (113 residues), 86.5 bits, see alignment E=1.5e-28 PF00196: GerE" amino acids 148 to 203 (56 residues), 63.4 bits, see alignment E=1.2e-21

Best Hits

Swiss-Prot: 42% identical to UVRY_ECO57: Response regulator UvrY (uvrY) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 75% identity to rfr:Rfer_0563)

Predicted SEED Role

"Regulatory protein, LuxR:Response regulator receiver"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (209 amino acids)

>GFF1472 Regulatory protein, LuxR:Response regulator receiver (Hydrogenophaga sp. GW460-11-11-14-LB1)
MIKVILCDDHAMVRRGIRDTISEATDIQVVGEAGSYPELRDLMRKSECDVLVLDLNMPGR
GGLEVLGTLKEEGSTVKTLVVSMYPEDQYAIRCLRAGARGYLNKAGEPAELVAAIRTVMQ
GRKYVTADVAQMLVDTLNAPESEELHASLSERELQTLQKIASGKKLSEIAEELMLSPKTV
SVYRARVLEKLHLANNAELTVYAIRNGIV