Protein Info for GFF1454 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Flagellum-specific ATP synthase FliI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 TIGR01026: ATPase, FliI/YscN family" amino acids 14 to 465 (452 residues), 566.1 bits, see alignment E=4.9e-174 TIGR03496: flagellar protein export ATPase FliI" amino acids 33 to 465 (433 residues), 633.2 bits, see alignment E=1.8e-194 PF02874: ATP-synt_ab_N" amino acids 38 to 97 (60 residues), 28.4 bits, see alignment E=3e-10 PF00006: ATP-synt_ab" amino acids 176 to 387 (212 residues), 288.7 bits, see alignment E=4.1e-90 PF18269: T3SS_ATPase_C" amino acids 397 to 465 (69 residues), 91.7 bits, see alignment E=3.2e-30

Best Hits

KEGG orthology group: K02412, flagellum-specific ATP synthase [EC: 3.6.3.14] (inferred from 76% identity to aaa:Acav_4289)

Predicted SEED Role

"Flagellum-specific ATP synthase FliI" in subsystem Flagellar motility or Flagellum

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (492 amino acids)

>GFF1454 Flagellum-specific ATP synthase FliI (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSDSIFGTESRWDNFMEDVRANAAVKTPLEVRGTLTRLAGLVLEAVGLKVPVGSQCLIDN
GHKDPVLAEVVGFSNDRAYLMPAGDTHGLSSGASVTPLAPYRTVPRVGQANKPPSPDDRG
TLRLPLGAGLLGRVVDSHGNPLDHQGPILNVDIEPMDRAPLNAMDRDPVREPLDTGVRAI
NSLLTVGRGQRIGLFAGSGVGKSVLLGMMARYTKADVIVVGLIGERGREVKEFIEDILGA
EGRQRSVVVAAPADAPPLVRMQGAAYATAIAERFRDDGLDVLLLMDSLTRYAMAQREIAL
AIGEPPATKGYPPSCFAKLPQLVERSGNGLNGKGSITAFYTVLSEGDDQQDPIADAARAI
LDGHIVLSRALAESGHFPAIDVEASASRVMHNVAGKVHLELARRFRSLYSRYQKSRDLIQ
LGAYVAGSDPETDRAIVLYPALQRFLMQDMHEAATLPESLRQMQAALQDDKDKAAPQRQT
RPNHNPYEGNAG