Protein Info for GFF1452 in Variovorax sp. SCN45

Annotation: Predicted gluconate TRAP family transporter, DctM subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 transmembrane" amino acids 31 to 58 (28 residues), see Phobius details amino acids 70 to 87 (18 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 180 to 201 (22 residues), see Phobius details amino acids 209 to 240 (32 residues), see Phobius details amino acids 260 to 281 (22 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details amino acids 342 to 366 (25 residues), see Phobius details amino acids 371 to 397 (27 residues), see Phobius details amino acids 418 to 436 (19 residues), see Phobius details amino acids 443 to 462 (20 residues), see Phobius details amino acids 474 to 498 (25 residues), see Phobius details amino acids 518 to 550 (33 residues), see Phobius details amino acids 562 to 582 (21 residues), see Phobius details amino acids 602 to 626 (25 residues), see Phobius details PF04290: DctQ" amino acids 47 to 173 (127 residues), 99.5 bits, see alignment E=2.2e-32 PF06808: DctM" amino acids 213 to 622 (410 residues), 352.1 bits, see alignment E=6.1e-109 TIGR00786: TRAP transporter, DctM subunit" amino acids 223 to 623 (401 residues), 293.3 bits, see alignment E=1.3e-91

Best Hits

KEGG orthology group: None (inferred from 93% identity to vpe:Varpa_3884)

Predicted SEED Role

"Predicted gluconate TRAP family transporter, DctM subunit" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (629 amino acids)

>GFF1452 Predicted gluconate TRAP family transporter, DctM subunit (Variovorax sp. SCN45)
MAHESTFEAAAFAGASANPLSGMASRIDRVLGAAVEAVAALLVLAEICVLFAGVVSRYLF
HAPLVWSDELASILFLWLSMLGAVVALRRGEHMRMTALLQKVRPPTRAMLDAFAIAASVA
FLVLIVWPSIDYAHEESFIVTPALEVSNAWRAAAIPAGIGIMLVMALLRLLRVCTGRQIA
FALVGTAALAGAFWLAAPVFATLGKLNLVIFFVVIVAATVLSGVPIAFSFALATFGYLAL
TTRTPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMARAMIQFLASLLGHVRGGLS
YVLIGAMYLVSGISGSKIADMAAIAPVLFPEMTKRGAKPGDLVALLSATGAQTETIPPSI
VLITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRREDLSGVQRYSKREIGKLLL
VALPAVLLPFVIRAAVVEGVATATEVSTIGIVYAAVVGLVVYRQFDWRRLKPMLVDTASL
SGAIIFIVGCATAMAWGLTQSGFSQDLARVMGTLPGGAYGFLAVSIVAFIVLGSVLEGIP
AIVLFGPLLFPIAKAAGVHEVHYAMVVIFSMGIGLFAPPFGVGYYGACAVSKVNPDEGIR
HIWGYIGAMLVGLVIVALFPWFSIGFLKF