Protein Info for GFF1429 in Methylophilus sp. DMC18

Annotation: putative MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 47 to 67 (21 residues), see Phobius details amino acids 76 to 98 (23 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 141 to 160 (20 residues), see Phobius details amino acids 165 to 182 (18 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 253 to 275 (23 residues), see Phobius details amino acids 287 to 305 (19 residues), see Phobius details amino acids 312 to 333 (22 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 373 to 393 (21 residues), see Phobius details PF12832: MFS_1_like" amino acids 14 to 379 (366 residues), 65.3 bits, see alignment E=5.5e-22 PF07690: MFS_1" amino acids 15 to 336 (322 residues), 96.9 bits, see alignment E=1.2e-31

Best Hits

KEGG orthology group: None (inferred from 58% identity to hse:Hsero_4626)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (411 amino acids)

>GFF1429 putative MFS-type transporter (Methylophilus sp. DMC18)
MRLFKRPADSRQWLAVMNFFMADVRDGLGAFLGVYLLAQSWQADDIGYAMTIGGLATMMA
GIPAGALMDRTHAKRLWLSVCAILMVVGCLVLLLWHSFAAIALSQAATGVVRAMIGPAIA
SISLGLVGSKYLSRQLGQNEAWSHAGSLVSVSVAGVLGYFWGLSAVFMLLAVMAVLALLC
IRRIRPQEIDYHAARGLESHAAVSDSSRAVWKALLQSRPLLMLACIMMLFHLANAAMLPL
LGQTMVSQGLVNASLFTALTVMIAQLVMIPMALLAGRYAEQFSYERLVTLALLALPVRGV
IASTWNSPWAVVPVQLLDGVGAGLLGVALPGLVAKMLQGSGHFNVGLGFVLTIQGLGAAL
SPAMAGWVAQRYGYAMSFTLLTGVAVLAILLWWQQARQTAAQSAAGLQAGT