Protein Info for PS417_00710 in Pseudomonas simiae WCS417

Annotation: fusaric acid resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 692 transmembrane" amino acids 14 to 34 (21 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 147 to 163 (17 residues), see Phobius details amino acids 367 to 388 (22 residues), see Phobius details amino acids 394 to 411 (18 residues), see Phobius details amino acids 421 to 440 (20 residues), see Phobius details amino acids 446 to 464 (19 residues), see Phobius details amino acids 470 to 490 (21 residues), see Phobius details amino acids 502 to 522 (21 residues), see Phobius details PF04632: FUSC" amino acids 13 to 673 (661 residues), 547.6 bits, see alignment E=5.2e-168 PF13515: FUSC_2" amino acids 26 to 157 (132 residues), 61.2 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU0137)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TWS4 at UniProt or InterPro

Protein Sequence (692 amino acids)

>PS417_00710 fusaric acid resistance protein (Pseudomonas simiae WCS417)
MNGFFTGFPPARDWFYGVRTFAASMIALYIAMLMQMPRPYWAMATVYIVSSPFVGPTSSK
ALYRAIGTFMGAAAAVIFVPMFVQSPYMLVVVIALWTGTLLFLSMHLRTANNYALMLAGY
TLPLIALPVVDNPLAVWDVAEARTEEIFLGIAVAAVVGAMFWPRRLMPVFDGSVAKWFAD
AQVYSQRFLTRNVEPDEISTLRGGMVATFNTLELMIGQLPHEGARPQTVRNTKELRGRMI
HLLPVVDALDDALYAIEHRAPEFLDKITPLLQATRQWLEGTQDAAPMESWRALRDQVDAL
QPQGEALDDRHTLLFSNALYRLGEWIDLWQDCRSLQAAIQCESQDTWRAVYRHWRLGRLT
PFLDRGLMFYSAFSTVTAIIVASVLWILLGWTDGGSAVILAAVACSFFASMDDPAPQIYR
FFFWTAMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICIGTLTVQPRFYLGMLLTLVNT
SSFISIQGAYDADFLNFANVNLAGPVGLLFAFVWTLIARPFGAELAAKRLTRFSWRDIVS
LTEPATLAEHRHMAAQMLDRLMQHLPRLALINQDTGTALRDLRVALNLLDLLAYSPRILG
VPRVLLNQVVEGVGGYFKACLKAGERLPAPSGLLMTLDRTRRALNGQGLQDEDDTRLHLL
HALAGLRLSLLPGVEFIGGTEMEAPLPDGAPL