Protein Info for GFF1394 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: ABC transporter, fused ATPase and inner membrane subunits (EC 3.6.3.27)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 597 transmembrane" amino acids 38 to 56 (19 residues), see Phobius details amino acids 80 to 99 (20 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 203 to 225 (23 residues), see Phobius details amino acids 291 to 315 (25 residues), see Phobius details PF06472: ABC_membrane_2" amino acids 27 to 315 (289 residues), 198.2 bits, see alignment E=2.8e-62 PF05992: SbmA_BacA" amino acids 34 to 365 (332 residues), 146 bits, see alignment E=2.9e-46 PF00005: ABC_tran" amino acids 401 to 533 (133 residues), 64.7 bits, see alignment E=2.2e-21

Best Hits

KEGG orthology group: K02471, putative ATP-binding cassette transporter (inferred from 62% identity to rfr:Rfer_0735)

Predicted SEED Role

"ABC transporter, fused ATPase and inner membrane subunits (EC 3.6.3.27)" (EC 3.6.3.27)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.27

Use Curated BLAST to search for 3.6.3.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (597 amino acids)

>GFF1394 ABC transporter, fused ATPase and inner membrane subunits (EC 3.6.3.27) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTTSAPAARPPSLWPTLKGIGAFAAPYFQSEEKWRARGLLLAVVLLNLGTVYMLVQINEW
YRVFYDALQEKNQPVFWEQIVKFCWLALIYIVLAVYKFYLTQILQLRWRVWLTDHYMSRW
LANKAFYRMELARFTADEHGNPDNPDQRIQEDLNLFTSYTVSLSMGMFNALITLVSFVGI
LWTLSGSITLPLPGFLGGGQVEIIGYMVWAAILYCAVGSAIAHWIGRPQVRLNFQQQMLE
ANFRHHMVRVREYSESIALDGGEQVERRHLDVRFRDVMGNYFALIRNQKQLTWFSSFFSQ
AAIIFPLIVAAPRYFSGAIQLGQLMQINSAFGRVQDSLSWLVDNYMSLAVWKATTDRLIG
FEKSLQHQSETRDKMALTESADGIRAQDLTVSLPGGSTLLAGVDLDVKPGDTVLLHGPSG
SGKSSLFRALAGIWPHALGRVGLPKDTMFIPQRPYFPDGRLRDALAYPDPAENYTDEALR
DALNEALLPALTDQLDREDAWSQKLSGGERQRLAIARVMLKKPAWVLADEATSALDEEAE
ATIYQRLVERVKQAHGAIVSIAHRSTLAAHHRQRWALRANEQAAAGGARYRLEVSSD