Protein Info for GFF1391 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 526 transmembrane" amino acids 32 to 55 (24 residues), see Phobius details amino acids 75 to 93 (19 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 216 to 239 (24 residues), see Phobius details amino acids 248 to 268 (21 residues), see Phobius details amino acids 289 to 308 (20 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 380 to 403 (24 residues), see Phobius details amino acids 422 to 442 (21 residues), see Phobius details amino acids 499 to 521 (23 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 35 to 435 (401 residues), 242.3 bits, see alignment E=5e-76 PF07690: MFS_1" amino acids 39 to 430 (392 residues), 194.3 bits, see alignment E=4.3e-61 PF00083: Sugar_tr" amino acids 43 to 210 (168 residues), 33 bits, see alignment E=5e-12 PF05977: MFS_3" amino acids 46 to 210 (165 residues), 28.5 bits, see alignment E=8.3e-11

Best Hits

KEGG orthology group: None (inferred from 87% identity to vpe:Varpa_3132)

Predicted SEED Role

"putative transmembrane efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (526 amino acids)

>GFF1391 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MAQIGKAPCDDTLILHGAGAQESACPEASKPWVLAAAIVGSSMAFIDGTVVNVALPAIQS
DLHATAFQAQWVVESYALLLAALLLVGGALGDLYGRRRIFAIGVGLFALSSVACALAGSV
QQLIAARAVQGIGGALLVPGSLALISAAFPEKERGKAIGTWSGFSGITAAVGPVLGGFLV
DHFSWTWAFLINLPMALLVLWIVWRHVPESRGASAAGGLDVWGALLATAGLGGIVYAFIE
APTQGWRAPAVLAALAIGVLGSAGFFVAERRVRSPMLPLGLLRIGNFSGANLLTLLLYAA
LGGGLYFFPLNLIQVQGYSATVAGAALLPFIFIMFALSGWAGQLVDRFGSRIPLVAGPSI
AAVGFALFAVPGVGASYWSGFLPAVVVLGLGMAVTVAPLTTTVMNAVGPEMAGVASGVNN
AVSRAAAVLAIAVFGAVMASVFDVTLADQLRELGASAQVSAFLEGERSKLAGATLPPGVD
AATAAALKRAVAESFVAGFRWVMLLGSGLALLSAASAWVMIRRTEP