Protein Info for GFF1386 in Variovorax sp. SCN45

Annotation: Uncharacterized transporter YebQ, major facilitator superfamily (MFS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 36 to 55 (20 residues), see Phobius details amino acids 66 to 88 (23 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 126 to 147 (22 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 224 to 241 (18 residues), see Phobius details amino acids 261 to 286 (26 residues), see Phobius details amino acids 298 to 319 (22 residues), see Phobius details amino acids 327 to 349 (23 residues), see Phobius details amino acids 355 to 372 (18 residues), see Phobius details amino acids 394 to 415 (22 residues), see Phobius details amino acids 422 to 443 (22 residues), see Phobius details PF07690: MFS_1" amino acids 5 to 404 (400 residues), 159 bits, see alignment E=7.9e-51

Best Hits

KEGG orthology group: K08169, MFS transporter, DHA2 family, multidrug resistance protein (inferred from 94% identity to vpe:Varpa_3137)

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>GFF1386 Uncharacterized transporter YebQ, major facilitator superfamily (MFS) (Variovorax sp. SCN45)
MLVIILGLIVSVLDGTIVNLALPGIARELQASPSQAIWVVNAYQIATLVMLLPLASLGDL
VGYRRVYLVGLAVFTLSSLAATFANSLATLTAARAFQGLGAAGIMSVNAALVRLTYPSSQ
LGKGMALNSLVVATSSVAGPSVAAAILSVASWPWLFAINVPLGIVTFALGMRALPFNRVA
PAAGLRFSPVDVGLNVLMFSLVFLGVDRLGVREGPVQGAGGSQASAWGILLAGLAVGFVY
LRRQRKQAVPLFPIDLLRIPVFALSMGTSVAAFCAQMLAYIALPFLLLDAYGRSHIEAGL
LITAWPLGIVVMAPIAGRLIGRYPDGLLGGIGLALLASGLALLAALPAHPGNADIAWRMA
LCGLGFGLFQSPNNHTIVTSPPAHRSGAASGMLGTARLTGQTLGAVVLAAVFSLWSPHGG
HGPVVALVLAACCAAVAAVFSSLRLKTTKPGG