Protein Info for GFF1379 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 108 to 132 (25 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 175 to 196 (22 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 276 to 296 (21 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 362 to 382 (21 residues), see Phobius details amino acids 397 to 417 (21 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 383 (364 residues), 153.7 bits, see alignment E=3.2e-49

Best Hits

KEGG orthology group: None (inferred from 91% identity to vpe:Varpa_3141)

Predicted SEED Role

"Nitrate/nitrite transporter" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>GFF1379 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MNPVEQRTISKISWRLLPLLMISYFIAYLDRVNLGFAGAAMSKDLGFTAAVFGSAAGIFF
LAYFLFEVPSNMALERFGARRWIARIMFSWGILSAAQAWVGGATSFNIVRFLLGIAEAGF
FPGVIFYITLWFPAAYRARIVGWFMFAIPISTVIGSPISGYILNMDGVGGMHGWQWLFIL
EALPSLVLTFFVLMYLPDGPKDAKWLTDEERTWLQRTLDAERQNRESINKISWKQSLLNP
RVIGLGFVYMGITVPLYGLSFFLPQIIKGFGGLSNVQIGFINAFPYLVGAVAMLFWTRAS
DARKERKWFLLIPLACIFVGLVLAAQTSSPVPKMAAVTLAAFGIFSALPTFWTLPTAILS
GTAAAAGIAWINSIGNLGGYIGPTIFGALKDRMGNDIYAVIFLALLSVVAFVLVLIIGHD
ARTEQAVAPGRA