Protein Info for GFF1369 in Pseudomonas sp. DMC3

Annotation: Methyl-accepting chemotaxis protein McpP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 205 to 229 (25 residues), see Phobius details PF08269: dCache_2" amino acids 36 to 199 (164 residues), 72 bits, see alignment E=1e-23 PF17200: sCache_2" amino acids 50 to 195 (146 residues), 73.9 bits, see alignment E=2.8e-24 PF00672: HAMP" amino acids 226 to 279 (54 residues), 49.7 bits, see alignment 7.7e-17 PF00015: MCPsignal" amino acids 344 to 524 (181 residues), 133.5 bits, see alignment E=1.5e-42

Best Hits

Swiss-Prot: 72% identical to MALCR_PSEAE: Methyl-accepting chemotaxis protein PA2652 (PA2652) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 95% identity to pfo:Pfl01_3768)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>GFF1369 Methyl-accepting chemotaxis protein McpP (Pseudomonas sp. DMC3)
MRLSLKAKVLSLAVLPVLLFALVISVTTLFILQEQARKEVEQTRERLLSDAKATLQSYVA
VAMTTIKPLYDAAAPGDDAARAQAIKLLSGIRYGKDGYFFGYDSETVRLFKANDPDGVGK
SFKDNRDPNGVYVNLGLVKVAKDGTHYLQYSSPLPGNAKVLVPKLGYTEYLPKWDMAVGT
SVNLDGIEAQVAQVEAQVQERVQGVVLSIVGVAVLVLLVIAAAGMLLANTILRPLTLMKA
NLDDIAAGEGDLTRRLNITSQDELGELAGSFNRFVDKIHGLVRQITEMTTQLTGLVTQVS
EQAQRSDQAMERQRHETDQVATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQSAKRVVA
GSIKQIHALVDDIRNSGVSLDSLQQDVSSIVGVLGVIRSIAEQTNLLALNAAIEAARAGE
AGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQQAVEAMRRSSEAGDGTSQQANQ
AGASLDAMAQLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDSVADETQLGAQT
SRSLAELGQRLGKLVGQFRI