Protein Info for GFF1367 in Pseudomonas sp. DMC3

Annotation: Methyl-accepting chemotaxis protein McpU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 715 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 362 to 383 (22 residues), see Phobius details PF00672: HAMP" amino acids 381 to 434 (54 residues), 37.4 bits, see alignment 2.6e-13 PF00015: MCPsignal" amino acids 499 to 682 (184 residues), 143.9 bits, see alignment E=4.7e-46

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 97% identity to pfo:Pfl01_3770)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (715 amino acids)

>GFF1367 Methyl-accepting chemotaxis protein McpU (Pseudomonas sp. DMC3)
MSLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSALVKASSMEMLTESAQARIES
QGEVQAAGIRQQFMDAYQYGHGFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANP
DLLGLSLVFEANALDGKDELFADQAELGSNDKGRFALYWSQPTPGKVTSMALPESDMSDT
STGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGHKVLMTSIVFPLQVNGKVIASLSVDI
NLNSLQAISQNASRKLYDGQTAVSIVSPAGLLAGYSPDAGKLSQRLDAVDQASGSELLRL
LAASTGVSSLHSNGQLKVLSPFQPIPDGPAWGVLLDVPEKVLVSRAEALKQQLDASNTSG
TLIELSLGLLAALIGLLLVWLMARSVTKPILGVAHMLEDIASGEGDLTRRLAYDKHDELG
QLAGWFNKFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASH
EMSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAA
NSEKIGTVLETIRAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEE
TRQVIEQLQNGTQEVVGSMGNSHRQAQGSVEQVGQAVTALRQIGDAVTVISDMNLQIASA
AEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQRLMDQFRV