Protein Info for GFF136 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 139 (21 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 207 to 223 (17 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 306 to 328 (23 residues), see Phobius details amino acids 334 to 358 (25 residues), see Phobius details amino acids 379 to 397 (19 residues), see Phobius details amino acids 436 to 457 (22 residues), see Phobius details PF07690: MFS_1" amino acids 3 to 386 (384 residues), 173 bits, see alignment E=8.5e-55 PF00083: Sugar_tr" amino acids 27 to 164 (138 residues), 54.7 bits, see alignment E=8.8e-19 amino acids 274 to 399 (126 residues), 24.1 bits, see alignment E=1.6e-09

Best Hits

KEGG orthology group: None (inferred from 88% identity to vpe:Varpa_2975)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (475 amino acids)

>GFF136 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MAMVAIEATIVSTVMPQIASELGGLHLYSWVFASFLLAQTAMTVVFGKLSDLYGRKPIMF
VGIAIFVLGSVLAGFAWSMPAMICFRLIQGIGAGAIQPVSLTIVGDLYPARERGKVQGYL
ASVWAVSAVVGPMIGALIVQKLSWAWIFWVNVPIGLAAAAGFWLYLHEAPSVRRSSIDIA
GAVLFTIGIAALMIALTDFGIGDTGSAALWTAVFAVTLVLFVMQERRAADPMVSLKLWGA
RIIATVNGAAMLGGMVLIGITTFLPMYVQVVLQRSSVTAGLTLTMVMLGWPIGATLTSRT
FHRIGLWRMVLIGGALIPVGTAAFALLSAGSTPLLAAVGSFIMGLGMGVMSLASLILIQE
AVDVAQRGVATASNVFSRNLGSALGATFFGAVFNFGLTRGDGAMAFTDDQLRLLLQGSHG
TAATDAGIRLALGGSLHLTFVTMLVVSLGVVALALLLPKEGLESHAIGAGKPAPK