Protein Info for GFF1352 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: GTP-binding protein EngB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 TIGR03598: ribosome biogenesis GTP-binding protein YsxC" amino acids 49 to 234 (186 residues), 198.1 bits, see alignment E=5.5e-63 PF01926: MMR_HSR1" amino acids 68 to 192 (125 residues), 63.8 bits, see alignment E=8.1e-22

Best Hits

Swiss-Prot: 79% identical to ENGB_POLSJ: Probable GTP-binding protein EngB (engB) from Polaromonas sp. (strain JS666 / ATCC BAA-500)

KEGG orthology group: K03978, GTP-binding protein (inferred from 76% identity to pna:Pnap_0663)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (262 amino acids)

>GFF1352 GTP-binding protein EngB (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTHRPTPAPQTASPSHDAPGLKAPIPRAGKTIDPLKPDPKIAHGWLHTARFLTTAPQLEH
LPPLDVPEIAFVGRSNAGKSTCINTLTQQKRLAFASKTPGRTQSINLFSLGKQGVTDAVL
ADLPGYGYAAVPREAKLRWQRVMGNYLLTRENLKGVVLLIDPRLGLTELDEILLEVIRPR
VEEGLKFLVLLTKADKLNHAEAQKALSIARLQSGGGEARLFSALKKKGLDEVALLLWQWT
HGATAPAQAADPVPDDEPPALD