Protein Info for GFF132 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: TRAP dicarboxylate transporter, DctM subunit, unknown substrate 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 56 (21 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 105 to 128 (24 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 183 to 206 (24 residues), see Phobius details amino acids 227 to 248 (22 residues), see Phobius details amino acids 254 to 272 (19 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 317 to 339 (23 residues), see Phobius details amino acids 346 to 363 (18 residues), see Phobius details amino acids 369 to 393 (25 residues), see Phobius details amino acids 413 to 435 (23 residues), see Phobius details PF06808: DctM" amino acids 17 to 430 (414 residues), 342.9 bits, see alignment E=1.3e-106 TIGR00786: TRAP transporter, DctM subunit" amino acids 28 to 435 (408 residues), 330.1 bits, see alignment E=8.5e-103

Best Hits

KEGG orthology group: None (inferred from 58% identity to bja:blr7841)

Predicted SEED Role

"TRAP dicarboxylate transporter, DctM subunit, unknown substrate 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>GFF132 TRAP dicarboxylate transporter, DctM subunit, unknown substrate 3 (Hydrogenophaga sp. GW460-11-11-14-LB1)
MCREPPMDRDLVALLGFVGMFALMAVRVPIGIAMGIAGVGGFALLSGTTPALNLLANVPL
SVLTDYNLIVIPMFILMGAFASHSGMSTELFKAGRAWLGHRRGGLALASIAACGGFSAIN
GSSVATAATMTQVALPEMRRAGYHPGFSAGLIAAGGTLGIMIPPSVIMVLYGIMTETDIT
KLFAAGIIPGFMAIGFYSVVVAVVARLRPDTMPRGERLGWGERFASLRPLWAVVVLFVFV
LGGIYGGLFTVQEAAGVGAIGTLAIGMLRGRLGWKQIKAALIGALRVSSAIMMIVVGAYL
FGYFLTITQFTQNAVEFLVHLPVGPYGVLALIMVGYLILGAVMDELAMILLTVPIVFPAM
MQLGFDPVWFGVIVVMAVTFGMICPPVGMNVFVINSIARDVPLGAIYKGTMPFIAVDVVR
LLILCAFPALSLWLPGFIE