Protein Info for GFF1317 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Oxidoreductase, aldo/keto reductase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF00248: Aldo_ket_red" amino acids 2 to 317 (316 residues), 224.5 bits, see alignment E=8.2e-71

Best Hits

Swiss-Prot: 91% identical to TAS_SHIFL: Protein tas (tas) from Shigella flexneri

KEGG orthology group: None (inferred from 99% identity to spt:SPA2873)

Predicted SEED Role

"Oxidoreductase, aldo/keto reductase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF1317 Oxidoreductase, aldo/keto reductase family (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MTFGEQNSEADAHAQLDYAIANGINLIDAAEMYPVPPRPETQGLTESYIGNWLAKRGNRE
KLIIASKVSGPARNNDQGIRPHQALDRKNIREALHDSLTRLQTDYLDLYQVHWPQRPTNC
FGKLGYNWTDSTPVVSLLETLDALSEFQRAGKIRYIGVSNETAFGVMRYLHLAEKHDLPR
IVTIQNPYSLLNRSYEVGLAEVSQYEGVELLAYSCLAFGTLTGKYLNGAKPAGARNTLFS
RFTRYSGEQAQKAVASYVDIAKRHNLDPAQMALAFVRRQPFVASTLLGATTMAQLKTNVE
SLHLTLSEEVLAEIEAAHQVYTYPAP