Protein Info for GFF1303 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1123 transmembrane" amino acids 56 to 71 (16 residues), see Phobius details amino acids 715 to 730 (16 residues), see Phobius details PF04257: Exonuc_V_gamma" amino acids 2 to 344 (343 residues), 385.1 bits, see alignment E=3.8e-119 TIGR01450: exodeoxyribonuclease V, gamma subunit" amino acids 2 to 1087 (1086 residues), 1498.7 bits, see alignment E=0 PF27451: RecC_4th" amino acids 448 to 648 (201 residues), 226.7 bits, see alignment E=4.4e-71 PF17946: RecC_C" amino acids 829 to 1049 (221 residues), 216.4 bits, see alignment E=6e-68

Best Hits

Swiss-Prot: 89% identical to RECC_ECOLI: RecBCD enzyme subunit RecC (recC) from Escherichia coli (strain K12)

KEGG orthology group: K03583, exodeoxyribonuclease V gamma subunit [EC: 3.1.11.5] (inferred from 90% identity to cko:CKO_04188)

MetaCyc: 89% identical to exodeoxyribonuclease V subunit RecC (Escherichia coli K-12 substr. MG1655)
Exodeoxyribonuclease V. [EC: 3.1.11.5]; RXN-19004 [EC: 3.1.11.5]

Predicted SEED Role

"Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1123 amino acids)

>GFF1303 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQWLQMTLSQKFGIAANI
AFPLPASFIWEMFVRVLPDIPKESAFSKQSMSWKLMTLLPQLLDKDEFVLLRHYLTDDTD
KRKLFQLSARAADLFDQYLVYRPDWLTQWEAGKTVEGLGEAQNWQAPLWKALVEYTAALG
QPRWHRANLYQRFIQTLESATACPPGLPSRVFICGISALPPVYLRALQALGKHIEIHLLF
TNPCRYYWGDIKDPAWLAKLMARQRRHSFEDRHLPLFRENQNPEALFNSDGEQDIGNPLL
ASWGKLGRDYIYLLSELENSQELDAFVDITPDNLLHRIQADILELESHAVAGVNLEEYSR
SDNKRLLDPEDNSLSFHVCHSPQREVEILHDRLLAMLEADPTLTPRDIIVMVADIDSYSP
FIQAVFGSAPTERYLPYAISDRRARQSHPVLQAFISLLSLPDSRFVSEDVLALLDVPVLA
ARFTINEEGLRYLRLWVNESGIRWGIDDDNVRELELPATGQHTWQFGLTRMLLGYAMESA
QGEWQSVLPYDESSGLIAELVGHLASLLMQLNIWRRGLAQERPLEEWLPVCRDMFNDFFL
PDADTEAAMTLIEQQWQAIIAEGVAAEYGDAVPISLLRDELAQRLDQERISQRFLAGPIN
ICTLMPMRSIPFRVVCLLGMNDGVYPRQLAPLGFDLMSQKPMRGDRSRRDDDRYLFLEAL
ISAQQTLYISYIGRSIQDNSERFPSVLVQELVDYIGQSHYLPGDETLTCDESEARVKAHI
TRLHTRMPFDAQNYQPGEQQSYAREWLPAASQSGKAHSDFVQPLPFTMPETLTLESLQRF
WAHPVRAFFQMRLQVNFRSEESEIPDAEPFELEGLTRYQLNQQLLNTLVEEDDAERLFRR
FRAAGELPYGAFGEIFWDAQCQEMQQLASRVIACRKPSQSLEVDLLCNGVQLTGWLPQVQ
EDGLLRWRPALISVAQGVQLWLEHLVYCASGGSGESRLFLRKEGEWRFPPLDKTQAMAYL
AQLIEGYREGMSSPLLVLPESGGAWIKACYDAENDVMLDDDDTLQKARTKFLQAYEGNMM
VSGEGEDIWYQRLWRQLESETLQAIIAQSRHYLLPLFRFNQSR