Protein Info for PS417_06465 in Pseudomonas simiae WCS417

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 PF00072: Response_reg" amino acids 8 to 115 (108 residues), 104.7 bits, see alignment E=3.2e-34

Best Hits

Swiss-Prot: 37% identical to ARCA_HAEIN: Aerobic respiration control protein ArcA homolog (arcA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 74% identity to pmk:MDS_3618)

Predicted SEED Role

"Phosphate regulon transcriptional regulatory protein PhoB (SphR)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UE34 at UniProt or InterPro

Protein Sequence (236 amino acids)

>PS417_06465 transcriptional regulator (Pseudomonas simiae WCS417)
MAKQDHLLIVDDDPQIRQLLCDYLSDAGFQVSTAADGKEMRRRLALNVIDLIVLDLMLPG
EDGLSLCRELRVNSNTPVVMLTAKGSLIDRIVGLEIGADDYLPKPFDPRELLVRIKVVLR
RVQSFPDRARLDEAPSIRFAGWQLDTRARQLLSPEGVVVSLGNSDYRVLRLLLQHPNRPL
SRDFLLNHVFDKDSTPFDRSIDVCVSRLRSQLPANVIKTVRNEGYMLTADDVVLES