Protein Info for GFF1262 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 63% identical to UGPC_BRUSU: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Brucella suis biovar 1 (strain 1330)
KEGG orthology group: K05816, sn-glycerol 3-phosphate transport system ATP-binding protein [EC: 3.6.3.20] (inferred from 85% identity to aaa:Acav_3572)Predicted SEED Role
"Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.6.3.20
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (334 amino acids)
>GFF1262 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3) (Hydrogenophaga sp. GW460-11-11-14-LB1) MASLSLRDIVKRYGSGPKANQVIHGVNAEIQDGEFVVIVGPSGCGKSTLLRMVAGLEEIS GGELRIGDRVVNNLEPAQRDIAMVFQNYALYPHMTNFDNMAYGLKIAKVPKEEIRARVDK AAKILELGHLLERKPRELSGGQRQRVAMGRAIVRQPQVFLFDEPLSNLDAKLRAQTRLEI QKLHRELGITSLFVTHDQVEAMTLAERMIVMNAGNMEQFGTPEEVYTRPATTFVASFIGS PPMNLLKHAPGGRAGSILGIRPEHIDIGNEGWTLKVETVELLGAERLVHTRLGDEAMIIR THEDQGAPAIGSTIHAKPREDRLHWFDAETGRRQ