Protein Info for GFF125 in Sphingobium sp. HT1-2

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 818 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07715: Plug" amino acids 52 to 158 (107 residues), 53.1 bits, see alignment E=4.2e-18 PF00593: TonB_dep_Rec_b-barrel" amino acids 254 to 782 (529 residues), 113.6 bits, see alignment E=2.2e-36

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (818 amino acids)

>GFF125 TonB-dependent receptor (Sphingobium sp. HT1-2)
MKQLLMCSAALVVAAAPATALAQSTGSQDFEDSIIVTGAQGDQSVGGVKIPETPKAKVTL
DQEIIARQRPGQAINETLNLVPGVSFSNQDPWGSLGGSFTVRGFSSDRVSQTIDGIPLND
SGNYALYTNQQLDPEIIEAATVSLGSTDVDSPTASAAGGTINIRSLMPSDEMGAMISASY
GNIVARGNDDDRAYHRIFGMFQTGVFTPFGTKAWFSASRATNKSTYTNYGGVDKQQYNGK
IYQPIGSNGDFIALAGHYNQNRNTFNGSTYTTATFPGTTDGRFYDTATCTVDTPQTGVTD
YANSCGSAFERRYNPSNTGNVRLNSRFTLANGLTLTVDPSFQYTKANGGGTSYAYEGASA
DGNTGGYYLKDSRNTATSSSTQYYYVGGVDLNGDGDTQDFVRVLSPSQTVTKRYGVIANL
SYDIDPDNRLRLSYTYDRARHRQTGEAGYLEANGDPVDVFPVNNPIVDADGNVVQKRNRL
SYATLNQISGEYRGSYLDDQVILLLGARMPFFSRDLNQYCVTTDASGNVNCPAIQAGIDA
QLAANSAYAAPQSRKFDYNKLLPNLGVTYKFTSKASVFTSYAKNLSVPGTDALYGALYFD
EGSSSGNPKPETSDAFDLGVRYQSGIVQAQLSGWYTRYNNRLATAYDADCDCSVTRNLGR
VDKYGVDGSVAVRPVKDLMLYVFGSYLKSEIKDDVQTGASTYAATAGKREAGAPVYTLGS
RIQGTLGPVDLGLQIKRTGERYVNDINTVKLPGYTLVDLDARFSLEQWGLKKTFFQLNVT
NLFDKVYIGYSGTGLTSTATTAYLGSPRAISGSMVVAF