Protein Info for GFF1229 in Methylophilus sp. DMC18

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF20123: DUF6513" amino acids 3 to 91 (89 residues), 105.4 bits, see alignment E=7.9e-35

Best Hits

KEGG orthology group: None (inferred from 71% identity to mep:MPQ_1684)

Predicted SEED Role

"Related to Dihydropteroate synthase" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>GFF1229 hypothetical protein (Methylophilus sp. DMC18)
MNRLLFLTGKLAEHSLHQVLQAIQADSKQSPFEYEVKQIGVSVAALMTPPLIARRLPKVE
NIDKVILPGLCQGDLGLLESQWGVPVERGPKDLKDLPQYFGQQGKVPDLSQHSVLIFAEI
VDAPDLTVEQIIAKAQHFKQQGADVIDLGCLPGKAFAHMTESVCALKSAGFQVSVDSMRE
DDLLAAGKAGADYLLSLHENSLWIAEEVASTPVLIPAKPGSMPSLQRAIEHCLKRELAFI
ADPILDPIHFGFTESIVRYHKLRKKYPDIAIMMGVGNLTELTDADTTGINAMLFGMISEL
NINAVLATSVSAHACEAVAEADIARRVMYRAKQDKRLPRGYDAGLLGLHDRKPFPYSAAE
IAEMARQIKDPSFRIMVSEAGVHVYNRDGLQQATDPYVFYPELQVQDDASHAFYLGVELA
RAQIAWQLKKRYVQDEMLEWGVASVAQNKQAKVAHREASIKERQEATKPDQASGATVHAS
AKKPVGNSTSPENKE