Protein Info for GFF1223 in Variovorax sp. SCN45

Annotation: Aldo/keto reductase, SMc04056 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 PF00248: Aldo_ket_red" amino acids 16 to 319 (304 residues), 236.8 bits, see alignment E=1.4e-74

Best Hits

KEGG orthology group: None (inferred from 92% identity to vpe:Varpa_2632)

Predicted SEED Role

"Oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>GFF1223 Aldo/keto reductase, SMc04056 family (Variovorax sp. SCN45)
LEYRHLGKSGLKVPVLSFGTGTFGGKGEFFSAWGSTDVAEARKLIDICLDAGVNMFDSAD
IYSAGAAESVLGEAIKGRPRDQLLISTKATFRSGKGANDVGSSRHHLVQAVDAALKRLGT
DYIDLFQLHGFDASTPVEETLSTLDDLVRAGKLRYVGASNFSGWHLMKSLAVSERYGYPR
YVAHQAYYSLVGRDYEWELMPLAQDQGVGAVVWSPLGWGRLTGKIRRGQPLPANSRLHVT
ADMGPPVPDELLYRVVDALEKVGAEVGKTVPQVALNWLLQRPTVSSVVVGARDEAQLRQN
LGALGWNLTPAQVAELDAASTTTRAYPYWHQQGFLERNPNAV