Protein Info for GFF1191 in Variovorax sp. SCN45

Annotation: Predicted hydroxymethylpyrimidine transporter CytX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 32 to 54 (23 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 100 to 119 (20 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details amino acids 213 to 234 (22 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 330 to 347 (18 residues), see Phobius details amino acids 353 to 374 (22 residues), see Phobius details amino acids 386 to 404 (19 residues), see Phobius details amino acids 410 to 427 (18 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 18 to 426 (409 residues), 49.9 bits, see alignment E=1.2e-17

Best Hits

KEGG orthology group: None (inferred from 90% identity to vpe:Varpa_2607)

Predicted SEED Role

"Predicted hydroxymethylpyrimidine transporter CytX" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>GFF1191 Predicted hydroxymethylpyrimidine transporter CytX (Variovorax sp. SCN45)
MAHDNNNDAIASNEALTPLPASRRVFGWHDHAALWFSLGVGLLVMQIGAYLVPAVGTRDA
AIAIVLGSCLGAGLLAWTARLGCESGLASAGLMHATYGSAFARLPVLLNIVQLVGWTTFE
LVVMREGTQAIGQAAFGPSIGSAWGGVLTTLLWGAVLLALLAGSMVKLVRRFVSRFGLPL
VVLSLLWLSWQFATRLHAKGLDAFWARPGDGSMGMFGALDLVIAMPVSWLPLVADYARHG
KRSTGGLGSAFSGTWLGYALANIWCYALGVMVVSVAEPGTELVTALLLAQGGLLALGLIL
IDELDNAYGDVYSGSVSTHSLLPRWSVKRWGLLLAALCIAFALVLPMHTLEPFLLLLSSV
FVPLYGVIIGRLGTGQSVPAGGTRKIDFGAALIWIAGIAAYHALAKWAPQFGSALPTLAA
TFALAWISRPSAQRGASALAQSRG