Protein Info for GFF1153 in Variovorax sp. SCN45

Annotation: Diacylglycerol kinase (EC 2.7.1.107)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01219: DAGK_prokar
  • amino acids 31 to 128 (98 residues), 108.2 bits, E=8.8e-36

Best Hits

Swiss-Prot: 48% identical to KDGL_ECOLI: Diacylglycerol kinase (dgkA) from Escherichia coli (strain K12)

KEGG orthology group: K00901, diacylglycerol kinase [EC: 2.7.1.107] (inferred from 91% identity to vap:Vapar_2363)

MetaCyc: 48% identical to diacylglycerol kinase (Escherichia coli K-12 substr. MG1655)
Diacylglycerol kinase. [EC: 2.7.1.107]

Predicted SEED Role

"Diacylglycerol kinase (EC 2.7.1.107)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.1.107)

MetaCyc Pathways

• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• phosphatidate metabolism, as a signaling molecule (1/5 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (6/17 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism
• Phosphatidylinositol signaling system

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.107

Protein Sequence (135 amino acids)

>GFF1153 Diacylglycerol kinase (EC 2.7.1.107) (Variovorax sp. SCN45)
MSALPNLPDPAVNPQKARKGFERVWHATLISLHGLRAGWSEPAFRQEAILSIFMIPASFW
LGSSWVEVALLAGSALLVMIVELLNTAVEAAIDRIGPEWHDLSKRAKDMGSAAVLLSLTL
CGGIWAAALWQRFLS