Protein Info for GFF1126 in Variovorax sp. SCN45

Annotation: Metal transporter, ZIP family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 23 to 43 (21 residues), see Phobius details amino acids 49 to 73 (25 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 119 to 144 (26 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 225 to 248 (24 residues), see Phobius details amino acids 254 to 273 (20 residues), see Phobius details amino acids 284 to 304 (21 residues), see Phobius details PF02535: Zip" amino acids 153 to 301 (149 residues), 82.3 bits, see alignment E=2e-27

Best Hits

KEGG orthology group: K07238, zinc transporter, ZIP family (inferred from 86% identity to vpe:Varpa_2523)

Predicted SEED Role

"Metal transporter, ZIP family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>GFF1126 Metal transporter, ZIP family (Variovorax sp. SCN45)
MNDPRQVTVAGTRARPGRPMREWIGLAIVAAGALVGLLQFWTFVRGDPIVWNALLGGSVA
ALATALGTLPMLFSQKLPDRLQDTLFGFGAGVMLAASAFSLIIPGLEAARNVGVFGGGSW
AAGGVIGSAILLGGAALMLMDRVLPHEHFIKGREGQTARQLRRTWLFVFAIALHNVPEGL
AIGVGYAANNGLRADALATGIAIQDVPEGLVVAVALLAAGYSRIFAVLIGMASGLVEPLG
AVLGAAVVGHSAMLLPWGLGFAAGAMLFVISHEIIPESHRKGHEAFATSGLMIGFVLMML
LDTALG