Protein Info for PS417_05520 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 589 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details transmembrane" amino acids 280 to 299 (20 residues), see Phobius details PF00672: HAMP" amino acids 298 to 349 (52 residues), 49.2 bits, see alignment 7.9e-17 PF00512: HisKA" amino acids 367 to 429 (63 residues), 51 bits, see alignment E=1.8e-17 PF02518: HATPase_c" amino acids 475 to 578 (104 residues), 89.8 bits, see alignment E=2.4e-29

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU1131)

Predicted SEED Role

"FIG00956137: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UAY6 at UniProt or InterPro

Protein Sequence (589 amino acids)

>PS417_05520 histidine kinase (Pseudomonas simiae WCS417)
MITKTRQKARPFAISRWSVQRKLVLAFWLVSVIPTMIAAELAATTLSQIFDSNVRIWLQE
STKIVKDEIGDILHDNARMAKLFLRYTSPPASKQAAKHDRLTADIADATDIDVVALIRTS
DQKIVFSTAASDIVKQISLAKNTVLQTVQVGGASTGIVVSTFETSQDGVDYELLVGTYLD
SSFLTSVADVHSLDLRLYLANPEGFSEIFSTQRFEDHPSRIPKSVETAMRATRQPSEQFT
NNYSGLYWPIFNDAGDLQGVIFSGLLRHTSLVGLVNQSNLFVLIFLLSSALSLAAGVLVS
RRLTKPLRDLSQGVSAVISGDYAHRVVVSGGDELAQLSSTFNHMTERLGELHHLEAQLRR
RDRLHALGEVAMGLAHEIRNPLGIIKTATQLLHRRADLADTDKRHLEYVISEVSRINDLI
TEFLDFAKPNPPLRVLLPARPLVEEILGFCAPELATHTIDAQIDDQAPGATIYADAKQLK
QACLNLILNAIDAMPEGGRLTLGIRADGENTVISIADTGQGIPADMIERIFTPFVTTKAS
GTGLGLAKVYSIMESHDGSIECASEKDAGATFSLYIPASGEDDEDSHDA