Protein Info for GFF1074 in Pseudomonas sp. DMC3

Annotation: HTH-type transcriptional repressor CytR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 PF00356: LacI" amino acids 4 to 48 (45 residues), 64.6 bits, see alignment 1.1e-21 PF00532: Peripla_BP_1" amino acids 61 to 314 (254 residues), 109.3 bits, see alignment E=5.1e-35 PF13407: Peripla_BP_4" amino acids 63 to 309 (247 residues), 59.9 bits, see alignment E=5.8e-20 PF13377: Peripla_BP_3" amino acids 167 to 328 (162 residues), 152.2 bits, see alignment E=2.8e-48

Best Hits

KEGG orthology group: K05499, LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG (inferred from 81% identity to pba:PSEBR_a3537)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>GFF1074 HTH-type transcriptional repressor CytR (Pseudomonas sp. DMC3)
LSNIREVARLAGVSVATVSRTLKSPERVLAPTRERVMAAVEQAGYRPNLMAVQFRSRRTG
NLVILVPTIANTFFARVISGAQQAAQAAGYRLLLCDTQGREELERQFAELVYAYQADGVI
QLRAYDPFENTPADADVPPIVNACEVLKAGRYPTISLDNVAAAKAMTDHLIALGHRRIGL
IKGSKNSPLTLDRLAGYEAALREAGIAFDEALICHGNFSLEAGFAGAQKMLALAERPSAL
FCENDEMAIGALKRIRQAGLRVPEDISVVGFDDIPMAAYCDPPLTTISQPAEAFGARAVE
MLIALIEKQPLTERHVVLPFELTPRSSTARIDNSGKR