Protein Info for GFF1059 in Methylophilus sp. DMC18

Annotation: Beta-barrel assembly-enhancing protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 PF13181: TPR_8" amino acids 21 to 52 (32 residues), 13.3 bits, see alignment (E = 6.6e-05) amino acids 55 to 86 (32 residues), 17.6 bits, see alignment (E = 2.7e-06) amino acids 88 to 120 (33 residues), 15.8 bits, see alignment (E = 9.9e-06) amino acids 156 to 188 (33 residues), 17.8 bits, see alignment (E = 2.3e-06) amino acids 190 to 222 (33 residues), 19.1 bits, see alignment (E = 8.7e-07) amino acids 227 to 256 (30 residues), 18.8 bits, see alignment (E = 1.1e-06) amino acids 259 to 291 (33 residues), 20.7 bits, see alignment (E = 2.7e-07) PF13432: TPR_16" amino acids 59 to 120 (62 residues), 24.8 bits, see alignment E=1.9e-08 amino acids 133 to 188 (56 residues), 32.6 bits, see alignment 6.9e-11 amino acids 196 to 258 (63 residues), 28.4 bits, see alignment E=1.4e-09 amino acids 264 to 310 (47 residues), 18 bits, see alignment 2.7e-06 PF14559: TPR_19" amino acids 133 to 194 (62 residues), 30.3 bits, see alignment E=3.4e-10 amino acids 236 to 298 (63 residues), 32.1 bits, see alignment E=9.7e-11 PF07719: TPR_2" amino acids 157 to 188 (32 residues), 23.6 bits, see alignment (E = 3.2e-08) amino acids 190 to 222 (33 residues), 23.2 bits, see alignment (E = 4.2e-08) amino acids 227 to 256 (30 residues), 28.8 bits, see alignment (E = 6.6e-10) amino acids 258 to 291 (34 residues), 25.1 bits, see alignment (E = 1.1e-08) PF13431: TPR_17" amino acids 178 to 209 (32 residues), 23 bits, see alignment (E = 5.6e-08) PF13374: TPR_10" amino acids 227 to 253 (27 residues), 17.1 bits, see alignment (E = 3.6e-06) PF00515: TPR_1" amino acids 227 to 257 (31 residues), 34 bits, see alignment (E = 1.5e-11) PF13414: TPR_11" amino acids 234 to 271 (38 residues), 34.5 bits, see alignment 1e-11 PF01075: Glyco_transf_9" amino acids 521 to 553 (33 residues), 24.2 bits, see alignment (E = 1.5e-08)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (620 amino acids)

>GFF1059 Beta-barrel assembly-enhancing protease (Methylophilus sp. DMC18)
MNNEAIAKLLKLIAADPQKWDAYQKLAGLMLQNQEFHAAEQYLLQAISLRPDLLELRVQL
GNLHMRTQQFKAAHECYKQAIALDAKQAQLYYLDARALKNLGRTQEAILRLRTAIKLDPQ
RLPAFTECTDLMLQLQQVDQAANVLRQAVVAHPEHAHFHYRLGVLCMQLQQTDDALLCMN
EAIRIQPDFADAYHQRALILQSQGKPQEAVLSFDEAIRYQPNLHLPYNNRGVVLCQLGKY
TEAIADFRLALQLNPGYAAAQCHLGLALYENRQHDEAYACLETALKLAPNHAQARYTMSM
LRLARGEFEAGWPLYAARFQVLADKHRPDLNLLWSSAGALVGKTILIWAEQTLSDTLQYC
RYLPMVQACKPNHLVLAVPEALFDLFNEYWAHDATILVVCQDGRSLPHFDVFCPMLSLPA
VFNTQLDTIPASLPYLGVEARHSEPWQQLLGPGRRLRIGLNWCGEATNKYDQWRSIPLFL
MAPLLNMEVEWHSLQKEFRREDHIMLKRFPMLECHHPELINFTATAGLIMQMDLVISVDT
AVAHLAAALGKEVWLLLPQHAHFRWLQQREDSPWYPGMRLFRQGDDEAWEQVIDRLHQAV
TDVLAQRHERLIASEQAAQD