Protein Info for GFF1056 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: sensory box histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 790 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 46 to 65 (20 residues), see Phobius details amino acids 218 to 238 (21 residues), see Phobius details PF00512: HisKA" amino acids 272 to 336 (65 residues), 61.1 bits, see alignment E=1.7e-20 PF02518: HATPase_c" amino acids 383 to 496 (114 residues), 104.1 bits, see alignment E=1.2e-33 PF00072: Response_reg" amino acids 521 to 632 (112 residues), 71.9 bits, see alignment E=9.8e-24 PF01627: Hpt" amino acids 697 to 762 (66 residues), 33.2 bits, see alignment E=1e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (790 amino acids)

>GFF1056 sensory box histidine kinase/response regulator (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRRLAVLDASARSNYTSVSCVAARAQRGGATEMSVAGNLYRGKARLWVALAIFSVLMLSP
TAVIQVKQSQLIHQLTNTQYDSITWQFFQLEREHVKLLRMLDRALEGKALPSADEFVELY
EIYVSRVNLIKEHQRTDLIDRSPVYVKLLSELDAIIALADPVFAQPEGLLSKVRELEDVS
RSLWEVEPTLREMSREASRATSLYLDERNFQIREQARALTVLTVLQVLLLLCLLVLLVRH
IKRQDLQYALLKNLSDDLESARLEAEHANQAKSVFLANMSHEIRTPFQGLMGMLNLLNTT
TLNGVQRDHVQTALDSAQHLLGVLNDILDISTIESGELKLLMSPLDLEDLVDNTQELMRH
AAIEKAVDLRFEYGERLPKWVRGDAMRIRQILFNLIGNAIKFTDHGEIKVSVDLRPGSNG
NVSIVIEDTGNGMDDATLDRLFTRFYQADNSFLRKTGGTGLGLEISRSLARLMGGDITVT
SKVGIGSRFEVTLDLPEATAPTPSRDDVKVESASYQRLRLLVAEDHSINLKYMNLLLDKM
GHDAVFCGNGLEALDLLQQQSFDAVLLDYHMPELDGISTAQAIRKMGGVSSHIKIMLVTA
DVVGEIKSRAEEAGVDCFVSKPLTLHDLNQALLSCGLLIPEAPKGNELSDPSDLTALLQS
LDAQFPLAVDLVAYQQLVPFATREVRAEMVALVLAPQSGSLDVLVNAMTAGDQPAIERAA
HNLKGAGMLLGLSSLVRAATEIESTATQLNSGDAAQWKAKLRHLGERSKNEISQWEMSVK
ETPLPVEPNR