Protein Info for GFF1043 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02630: SCO1-SenC" amino acids 69 to 192 (124 residues), 41.4 bits, see alignment E=6.9e-15

Best Hits

KEGG orthology group: K07152, (no description) (inferred from 85% identity to pol:Bpro_1264)

Predicted SEED Role

"Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (227 amino acids)

>GFF1043 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone (Hydrogenophaga sp. GW460-11-11-14-LB1)
MMGRTTALSVLIALLAYAAGAWLTHDFQVWTAEGSRRLDVARAPVSAPHTPLHGPDMADT
ALPLLLAADGGVTIVDFFYTRCQTICLALGSSFQQMQAHIQEGLRKGPADAKNAPDVRLL
SISFDPAHDKPAALAAYAHRLKADPRIWRFATAHDETALRPLLERFQVVVIPDGMGGFEH
NAALLVVDGRGRLVRIFDYADMDTALAWAQHLAATQPKAAKAEGIAG