Protein Info for PS417_05070 in Pseudomonas simiae WCS417

Annotation: serine/threonine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 29 to 47 (19 residues), see Phobius details amino acids 53 to 72 (20 residues), see Phobius details amino acids 103 to 122 (20 residues), see Phobius details amino acids 142 to 159 (18 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 209 to 232 (24 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details amino acids 299 to 317 (19 residues), see Phobius details amino acids 346 to 364 (19 residues), see Phobius details amino acids 369 to 370 (2 residues), see Phobius details amino acids 375 to 393 (19 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details TIGR00814: serine transporter" amino acids 22 to 417 (396 residues), 547.9 bits, see alignment E=7.3e-169 PF03222: Trp_Tyr_perm" amino acids 34 to 391 (358 residues), 31.1 bits, see alignment E=7.3e-12

Best Hits

Swiss-Prot: 71% identical to SDAC_ECOLI: Serine transporter (sdaC) from Escherichia coli (strain K12)

KEGG orthology group: K03837, serine transporter (inferred from 96% identity to pfs:PFLU1034)

MetaCyc: 71% identical to L-serine:H+ symporter SdaC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-71

Predicted SEED Role

"Serine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions or Threonine anaerobic catabolism gene cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TV29 at UniProt or InterPro

Protein Sequence (428 amino acids)

>PS417_05070 serine/threonine protein kinase (Pseudomonas simiae WCS417)
MTDVRTPAAENPAATTTVTTGWTQYDTTWMLGLYGTAIGAGTLFLPINAGVGGFWPLIVL
ALLAFPMTFFAHRGLTRFVLSGKSGDITEVVEEHFGVGAGKLITLLYFFAIFPILLVYSV
ALTNTLGSFMEHQLHMTPPPRAILSLVLILGLMAIVRCGQGVIVKAMSVLVYPFVASLLL
LAFSLIPNWNGAFFASAGDGMPMPLFFKTLWLAIPVMVFSFNHSPIISAFAVDQKRVYGA
QAERKSSGILATAHGMMVLTVMFFCFSCVLALSPADLAAAKAQNISILSYLANHFQTPVI
AYAAPLIALVAITKSFLGHYIGASEGFQGLIVKSLRGRNRSMSAKWLERCTALFMVLTCW
AVATFNPSILRMIETMGGPIIACLLFLMPMYAIRRVPSLRKYSGQVSNVFVVVIGLIALS
AIVFSVLP