Protein Info for Echvi_4657 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 849 transmembrane" amino acids 14 to 36 (23 residues), see Phobius details amino acids 301 to 326 (26 residues), see Phobius details PF00512: HisKA" amino acids 352 to 417 (66 residues), 65.9 bits, see alignment 4e-22 PF02518: HATPase_c" amino acids 464 to 574 (111 residues), 95 bits, see alignment E=5.8e-31 PF00072: Response_reg" amino acids 596 to 707 (112 residues), 60.2 bits, see alignment E=3.2e-20

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G3K6 at UniProt or InterPro

Protein Sequence (849 amino acids)

>Echvi_4657 Signal transduction histidine kinase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKSTETTHKARKKVIIGFMLAIMLVLSVGAVTYFSLNRLLGTVETLSEPSDRMQELNALL
ADVYQLDKVKGNFEPENDTSVAVNYLDKIEKKLNYLEQFANDTVELNHLKQINYNINELV
VVYNGLREVKHNLINRNFSREALKNLETKIKRQEEINRLQNLGKIRFDHKIRRAKGRLDS
PAQKKVSAEEKFKDGNLMTEAEVENLRDMFQQFRPKVDEQDTINDASTSYSDSVLYAVKQ
FLVNINYEEQHLRSNLAQLEKELNEKNRALIEDTQTVISNLQYDALAEVEQKNASLYDLA
FDVAILLGVIIFVGIVGSSAFIYSILTEINKDESKRFELERAKVRSDKLAKAKQNFLANM
SHEIRNPLHAIQGYNDAIRKTPMTKDQEDYVNMVGFAADTLSGIVNDILDLSKLEAGKIT
IENEPFNPQKLFRAIQSSFELKAKEKQIDFVWTIDIPEEKWFSGDELRIRQILNNLISNA
LKFTEEGMVAVKVAYEKNFLWVNVKDTGIGMSEEFKENVFKEFNQGDGSINRKYGGTGLG
LAIVKRMLDLLKGKIELESSVGEGTEFKVKIPVKPTEAAVKVEEISSWYDLRGVNILLVD
DDSVGLKFAKLLLESNGAKVYDYLGGVKVRDEFEQVPLDLALLDVQMPEVTGYDTLRLMR
GKYGYTDLPAIAITANVFAKEKDQLSDAGFDAIVLKPFKEGDLVKRIGKVLELETISHEV
NGYSHAELLAQESQSYSIADISKFCMNDEEMVKEVLIDFCSSTSADLVELDQACVRGDWE
ELMEIAHKLGSRLGQLKIKASTLARGLEYDLKENNFNNAATMVEKIKKETLVVLDQIVVD
FQLFSRVPD