Protein Info for Echvi_4649 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Type III restriction enzyme, res subunit.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 643 PF21138: SMUBP-2_HCS1_1B" amino acids 11 to 112 (102 residues), 32.9 bits, see alignment E=2e-11 PF13604: AAA_30" amino acids 182 to 245 (64 residues), 43 bits, see alignment E=1.8e-14 PF04851: ResIII" amino acids 182 to 246 (65 residues), 25.7 bits, see alignment E=4e-09 PF13086: AAA_11" amino acids 182 to 403 (222 residues), 196.9 bits, see alignment E=2.2e-61 PF13245: AAA_19" amino acids 187 to 339 (153 residues), 34.6 bits, see alignment E=8.4e-12 PF13087: AAA_12" amino acids 411 to 612 (202 residues), 182.4 bits, see alignment E=3.1e-57

Best Hits

Predicted SEED Role

"putative helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G725 at UniProt or InterPro

Protein Sequence (643 amino acids)

>Echvi_4649 Type III restriction enzyme, res subunit. (Echinicola vietnamensis KMM 6221, DSM 17526)
MSRIQEELKITLQLLKKEWKEDLEQYRAKTLSASVADKQKEGICWYPVQLVKTKVGLGDR
LIVEVERADTRLSHGFQSGKTVSLFSNFSDGAPLRTNGVVNMVKKNTMVVTLMGHEWPDW
LHDGKLGVDLHFDEASYREMEYAVQQVIKAGEGRLGQLRNVLLGQEKASFVRGLPKSVEA
PHLNHSQVEAVEMVLAAQEVALVHGPPGTGKTTTMVQAIEETLRSHRQVLVCAPSNAAVD
LLVEKLLAIGLSTLRIGHPARVDDELLEQTLDAKIAQHSSFRDLKKLRKAAEEYRKLGRK
YKRNFGAAERQQRKQLFAEASKVKEAARHLEDYILYDVFQQNQVIATTLVGANHPVLKGM
AFPVVFIDEAAQGLEPATWIPVLKAQKIVMAGDHCQLPPTIKSYEAAKDGLSETLFEKVI
QRQPEASRMLRVQYRMPELIMRFSSEYFYHGQLEAAALTDEHFLGHDERVMAYIDTAGSG
FGEHLEKDSLSKLNTDEARFGLGMLEKLVEKIGVSTFKEKAFTIGVISPYKAQVKKLAEL
MEEGSEYENLRQLSDHVTIGTIDGFQGQERDVVLISMVRSNDEGEIGFLADTRRMNVALT
RAKRKLMVVGDSGTLSTHPFYQKFLDFVNDNGLYSSIYEYMEF