Protein Info for Echvi_4514 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Ribulose kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 PF00370: FGGY_N" amino acids 6 to 279 (274 residues), 51.9 bits, see alignment E=8.5e-18 PF02782: FGGY_C" amino acids 289 to 503 (215 residues), 123.7 bits, see alignment E=8.7e-40

Best Hits

KEGG orthology group: K00853, L-ribulokinase [EC: 2.7.1.16] (inferred from 50% identity to fjo:Fjoh_1119)

Predicted SEED Role

"Ribulokinase (EC 2.7.1.16)" in subsystem L-Arabinose utilization (EC 2.7.1.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.16

Use Curated BLAST to search for 2.7.1.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G567 at UniProt or InterPro

Protein Sequence (557 amino acids)

>Echvi_4514 Ribulose kinase (Echinicola vietnamensis KMM 6221, DSM 17526)
MSKNFVIGVDFGTDSVRSILVDTLDGKIVKSAVYRYPRWSKKLYCDAGSHQFRQHPLDHL
EGLEHTVSAIIRDSGIDPDSVKGIGVATTGSSPIPVDENGDALSMSSRFSNNPNAMVVLW
KDHTAVAEAEEITKAAKNGEVDYTAFSGGSYSSEWFWAKILSVYKKDPGVARNTCTWMEH
CDFIVGQLTGERPLNLKRSRTAAGHKAMWNKKWSGLPPASFWGGISPELGSLRETLYEQT
FHGSEKAGHLCSKWAEKLGLSADTAVAVGTLDAHAGAVGAGISPNTLVKVVGTSTCDILV
GSPTDPELDPIEGICGQVEDAVLPGTIGLEAGQAGFGDVLAWFAEVVLGPSRQIIHRSTQ
LDAVIKETIIEELEHSILDELSREALELAPCLNGASALDWINGRRSPFAKETLKGAFLNL
HMGTQASHMFRAMVEALCFGSKKIIDHLEGKGLTVEEIIAIGGVANKSPLVMQTMADIIG
KPIKIAASKEAPALGAAIHAAVASKVYPSMDQAVAKMVPAFKKVYSPDLQHQQVYVEKYK
MYEREGEVVENLKLTTQ