Protein Info for Echvi_4388 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 72 to 88 (17 residues), see Phobius details amino acids 100 to 124 (25 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details amino acids 183 to 203 (21 residues), see Phobius details amino acids 215 to 233 (19 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details amino acids 297 to 315 (19 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details PF00953: Glycos_transf_4" amino acids 74 to 227 (154 residues), 143.4 bits, see alignment E=3.1e-46

Best Hits

KEGG orthology group: None (inferred from 37% identity to mtt:Ftrac_2655)

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4W4 at UniProt or InterPro

Protein Sequence (384 amino acids)

>Echvi_4388 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase (Echinicola vietnamensis KMM 6221, DSM 17526)
MYIVFSSILAFCIGLIIFPFLIRWIKQSNLMDLPGGRKIHKAAIPSMGGIGILIAFALII
VLDIAHIPIGKYQYLLVSMAVLFLIGFLDDWKELSALQKLIGQLLAFTLVVVLGEVRLVS
FYGLLGIGELPLWLSYGLSIFLFVGLTNAYNLIDGLDGLAGTLGLISCSFLGAWFLATKH
MSEGVICLVMAGSLLSFLVYNWYPAKIFMGDTGSLPIGFFVTVFLLIFVQYNGILPDYSF
YKFQAPITAGLIMLVICCYDTLRVFVRRLKKGKSPFAPDKSHVHHFLIRMGYRHDQVALF
LGGIKCGLIILVLFLKDVQEIFLLPGVVLLVVAMGSMLNALTLRRVREKVKNAPRVLAKS
PYTVQKIQKEYNKVGDNPSLEIGK