Protein Info for Echvi_4379 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 332 to 354 (23 residues), see Phobius details PF02518: HATPase_c" amino acids 495 to 606 (112 residues), 78.7 bits, see alignment E=2.2e-25

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5J7 at UniProt or InterPro

Protein Sequence (610 amino acids)

>Echvi_4379 Signal transduction histidine kinase (Echinicola vietnamensis KMM 6221, DSM 17526)
MAISKRALLVSNRIGYERGVLAALINIGTAHYEKGNFKEAIVVEKDAMAQAEKLGFRKEI
GVLCINLSMVYLDIGLYEKAQQLAYRGLEIATQNGFDKQVARNHWTIGQVHELQGNLREA
RKSYTLSKSLYDRSGYHDIQHMLDIRIGRSYLQENLHAKANEFYERALKESRGGHRAGMV
RSYMALGDLLEQTGNPVTAMEKYAEAINIAMKMGTEQKVAEADLKIAKCLLEAGKPTEAY
VQVQRGLHMARKINHIALTREGLLVLSGIQAAKGDYKAALDSYQEYTLLGDSLMNQEVRI
QLVRAEEQFRHDQAIKTVNQKHREQLLRQRNFTYFILVLSILLVLMVLLLFLYLRNIRRT
NRIQKKHQEEMDAQNRELERMGNFKDRILSVVAHDVKTPLNSLKSTIDMYQEGMFTKEEM
EMLTKEIGTKLSEVNYFVKDLVLWAKSQMTETSARPVRFEIKEIVKKTISLLLPDATKKG
IEIIDRTGPRMVLADVEMVKIVVRNFLANAIKYSGQGDQIIINNKTNSGGRLLMVSVVDT
GTGIPAERLPHIFDEVNMSTEGTHHEIGTGLGLVLSRQYIEMNNGKIGVESEQGKGSTFW
FAIPLDEQPS