Protein Info for Echvi_4323 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Fe2+-dicitrate sensor, membrane component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 transmembrane" amino acids 76 to 98 (23 residues), see Phobius details PF04773: FecR" amino acids 110 to 202 (93 residues), 67.7 bits, see alignment E=1e-22 PF16344: FecR_C" amino acids 248 to 315 (68 residues), 36.1 bits, see alignment E=5.2e-13

Best Hits

Predicted SEED Role

"putative anti-sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G6A4 at UniProt or InterPro

Protein Sequence (323 amino acids)

>Echvi_4323 Fe2+-dicitrate sensor, membrane component (Echinicola vietnamensis KMM 6221, DSM 17526)
MNKGEFERLLEQQAKGKTTPEEEEAIRQAYKKIYFSQKPLQWNDRLAEDVKGRLEHNLAS
KMTLGKRNRPFIRLKPLVKVAAVLALVILGGFLAGKYVTLLPKAELITKRTTASQRATIT
LSDGTKVHLNVGSAITFPEQFYGEHRKVTLEGEAFFEVTRDVQKPFIVETASLSTKVLGT
SFNINAHESQTEMVTVVSGKVQVSQTAKPEMKAILLPDEAVVFNRSSGSLNKQRADAGQV
LDWKKEYIEFDKVSFKDAIRLLGQFYHTEIILENFQNDHCQIRAICKNNGIEHLLGQLQL
LVDFDYRIQKDGSIVIDYHGCKK