Protein Info for Echvi_4322 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1172 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 131 to 1172 (1042 residues), 824.3 bits, see alignment E=2e-251 PF13620: CarboxypepD_reg" amino acids 132 to 198 (67 residues), 36.7 bits, see alignment 9.2e-13 PF13715: CarbopepD_reg_2" amino acids 133 to 215 (83 residues), 66 bits, see alignment 5.1e-22 PF07715: Plug" amino acids 223 to 330 (108 residues), 70.8 bits, see alignment E=2.6e-23 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 306 to 336 (31 residues), 58 bits, see alignment (E = 6e-20) PF00593: TonB_dep_Rec" amino acids 583 to 1126 (544 residues), 31.5 bits, see alignment E=3.6e-11

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G6Q1 at UniProt or InterPro

Protein Sequence (1172 amino acids)

>Echvi_4322 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MKIYLRKRIVILTKHTFRVFLIQLVCLQALLANPSNSQGLEDYHVRVDAHKASLVEVLSG
LEHQTDFRFAYNQKLIQSQQKITLKLDADLRTVLKKITEQCDFQFRRIDESIFVTAVNTQ
DKSRKPVEEDRTLKGKVIDAETDEPIVGGTIIVEGGSKGTVTDLEGRFELTVDGKARRLR
VSFLGYEPKTIEIGNQNQFTISLSPKEGVLEEVVVVGYGEQKKANLSGAVDNIGGKSLSA
LQVNTIGEALLGQLPGVYVDIADGKPGRAAGFNIRGSTSINGGGPLIVIDGVPQTTNDLN
NISPHDIEEISVLKDAASTAIYGARASFGVILVTTKRGNEAMSVRYDNYFGFSKPTRVPE
LYDNPLDYLSINENEFNANIGHNYFTDAQIAYPEQVAADPSLPHATVEDIGGRPNLLLGG
QVYNYYDLWFRDLTPKQNHRFSVGGKDKKFQYYLSGDFNHEEGALSFKPEKINRYTLRSN
ITYNVTENLSVFNSTSLVKRDEEHPNQYLYGFTSNVWRFIENSNPMMPEYVEIDGEMVPT
DIGFYREFVENQSGIEQAMHDTKSTIGVDWKILGGKLKLHVDGTYQFTNTEKLRWWDNTG
PYLSNSFNNRNIVLDYYADAGPSKIYRSRWRTIRNNINAYGTYDTSYGLHNLTVMAGYNQ
ESYNYLYSYADREYPLQVPQHSLNLASGVANVSDDDDKNASRSVFTRINYNWNGKYLLEI
NGSYFLSSKFAKENRGHAFIAGSGAWRISEESFFDNIRSTVNNVKLRVSYGSIGNANIGS
YDYIPIMGVSQSAYTLEGERVNYTSSPNPKSANFTWETVETLNFGLDATFFRNRLTTTLD
VYQRNTDNMLANFRSLPSVFGATVPKENIASLKTQGWELNLAWNDTRKVGRNPFSYGVRF
NISDYHSEITDYYNPTNYLADYYRGQQLGEIWGLTTEGYFQTDEEAQNGALLETNSYKAY
AAAGTIKFQDINGDGVINFGERTLENPGDYRKIGNTTPRYQYGITLNGAWKGIDLNVFFR
GVGKRDIYPGAEAVNFWGPYNRKYQVMLQHTVDERWTPDNPDAYFPRPQGYLALGNNDLG
VPQTKYLQDASFLRLKNLTVGYTIPSSLTERIKISHVRVYFSGQNLWETTALHFSLDPEG
LTKDPDANESRVGLGTAYPIQRVFSFGLQVKL