Protein Info for Echvi_4159 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Putative regulator of cell autolysis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 40 to 62 (23 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 105 to 126 (22 residues), see Phobius details PF06580: His_kinase" amino acids 146 to 222 (77 residues), 73.9 bits, see alignment E=4.9e-25

Best Hits

Predicted SEED Role

"putative two-component system sensor protein, no kinase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4V6 at UniProt or InterPro

Protein Sequence (332 amino acids)

>Echvi_4159 Putative regulator of cell autolysis (Echinicola vietnamensis KMM 6221, DSM 17526)
MKNSFISRPAFYALHFLFWLCYGAILYAALSGWIYSSEQLWGAVISDVLTSSSIAYLNYY
VLLPRLYRKGKYSAYILASIGIVVGIVLLRVNLLGMSHRSVTYTYFIRSVPAIGFYLITT
VIWFFANMISAQRKEIELRNSQLASELKFLKLQLSPHFLFNTLNNIYSMAYFKEHNTASA
IMKLSEMMRHMLYEDQGRFISLNREIVFMENFIELWRLKLDEKPIIVFKHEGVKDRHRIA
HLIFLVFLENAFKHGNTMDGRIDIKLEIDAKENLHFYIKNDIIDARKTAEQESGVGLSNV
KKRLNLIYPGKHELILDQDATSFEVKLTIDLK