Protein Info for Echvi_4079 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01464: SLT" amino acids 103 to 209 (107 residues), 111.9 bits, see alignment E=1.3e-36 PF01476: LysM" amino acids 349 to 390 (42 residues), 50.5 bits, see alignment 1.6e-17 amino acids 421 to 463 (43 residues), 56 bits, see alignment 3.1e-19

Best Hits

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5J4 at UniProt or InterPro

Protein Sequence (464 amino acids)

>Echvi_4079 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) (Echinicola vietnamensis KMM 6221, DSM 17526)
MSNWKLLTLLSPMIFCVAIASAQNQGENGFIAAEEEVIQPTYHYEFIPDFTYDEVDQRVK
KMDTGMPFELNETIFAFINYFTVRNREYSKMTLARKEIYFPLFEKELKEHDMPEEIKYLA
IIESGLNPKAKSRVGAMGLWQFMPATGRVYDLHVTRDVDDRMDPELATEAACRYLKSLHR
MFDDWELALAAYNCGPGNVRKAIRRSGGKRTFWGIYNWLPRETRGYIPQFQAIMYVFNYA
DEHNLILEDGTFPIAHEKVRFDQELDLKRLADISGTCLEELEFLNPAIQNSKIPASSNYY
ALRVPKAKADYIASNVHWMMDSINLQEERLLAEQKTAAPKEKEPEKIIYKVRRGDALGKI
ARLYGTTVADLKTWNGLYSNNIKIGQHLTIYQDGDAFTRNLAADNPSQQDATFVKGSPKT
YVVQPGDSLWLIANKLDGVTIEEIKRLNKLSNNKIKPGQKLIIG