Protein Info for Echvi_4051 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1088 PF00580: UvrD-helicase" amino acids 11 to 441 (431 residues), 125.6 bits, see alignment E=6.2e-40 PF13361: UvrD_C" amino acids 456 to 626 (171 residues), 30.6 bits, see alignment E=5e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4L3 at UniProt or InterPro

Protein Sequence (1088 amino acids)

>Echvi_4051 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) (Echinicola vietnamensis KMM 6221, DSM 17526)
MEAKPFIIYKSSAGSGKTYTLTLEYLKLALAQPMAFRGILAVTFTNKATQEMKGRILEVL
GRLKNEVRPQEFLDQQLMQHLQLDEEGLKSRASVVLSAILHDYANFSVSTIDSFFQKVVR
AFAREIDLQAKFDVALDQAAVLERVVDRVVQHVMDDPYLHKWLVDYALTKIQEGRSWDIR
SNIRDLGMEIFTENFKQYQQLIREFLSSEQNLDIFRNYLNTKKQALYKKASEMKMEANSI
RQQFGLEWTDFPYGRRSFAMLFDKLGEHTNPIPELTESRKVAIDNESKWYSKTSKQKDAI
ISAYHAGLGDIYREFVPLRKEWLTYQAIDMNFYAYGIFRNLLEELRDLKDEENILMISDA
NDFLKEITKENDAPFIYEKVGNQYKHFLIDEFQDTSGFQWDSFKPLLENSLGYEHTNLVV
GDVKQSIYRWRGGDMKLLLEKVEEDIGPSSIQVKGLDTNYRSLPNVVAFNNALFSALPAQ
LESTFERETGHQRPGILTKAYQDVAQKVPSAKNEGDFKGLVRMEFLETSNEEEEPGYEEA
VLAKIPEMVMTLQDQGYRPKDIAFLVRKKHQGAMITDALMAYKHEHPELEYSFDVVSDES
MFLSKAATVKALIAALNYLADPADPVPFQTMWFYWSSLNGKPISHEVFSSLEKPAWLAEK
IAAFEKEEQRIARLPLMELLEELVDILGFNDLRTELAYISGFKEAVYDYVANNRADLSGF
LNWWEENSEKRTVKIPEGHDAMPIMTIHKSKGLQYKVVLMPFLTWRIVDYSKDNIIWSPF
RDTAEDVEAVIPLTLKKELADSIFQPVHLEEVTMAYLDTLNMIYVALTRAEEVLWTLSPK
KVVKQTTKISLNSLEKNLLELVEQGKLKTDSHDFSECFDQDLNVFEWGAWPEGSRASPAI
RPAEDQWLTWNHRHWGELLEVKKYAVDFSEEGLAQRHKRSFGLLIHELLEKSDSHQAAMD
QLQAFYFEGRLDQEERSLVSEQLDKLFINEQFRSWFEGEGRVLTEQGVILPGGRQKRPDR
IVIKDNVAEVVDFKTGEELDKYQRQVREYMQLVAGLGHFQVRGFLCYLETGKIVEVSATN
GGQYGLFD