Protein Info for Echvi_3993 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Predicted proteasome-type protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 PF00227: Proteasome" amino acids 4 to 184 (181 residues), 36.3 bits, see alignment E=2.3e-13

Best Hits

KEGG orthology group: K07395, putative proteasome-type protease (inferred from 57% identity to cts:Ctha_2387)

Predicted SEED Role

"proteasome-type protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5T2 at UniProt or InterPro

Protein Sequence (247 amino acids)

>Echvi_3993 Predicted proteasome-type protease (Echinicola vietnamensis KMM 6221, DSM 17526)
MTFCLGIKTKHGIVGLSDTRITSGSETTTSKKVYVVNKKKHSFFVMTSGLRSVRDKAITY
FTEVIEQQDDQFNKLYKTVNELGNQIKRVAKEDKKDLDESGLDFNLHAIIGGQLEEDSEP
KLYLLYPQGNWIEIRRGTPFVIIGNSGFGNPVLRRSITYEETLDFAIKSAFLAFDATRIS
ANDVDFPIDTVTMENGAFHIHENRFEQNELLHISDFWNSRLKKAVSDLPADILNRALQDS
ESPIDEF