Protein Info for Echvi_3914 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Transcriptional regulators

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 PF00356: LacI" amino acids 8 to 55 (48 residues), 36.3 bits, see alignment 7.6e-13 PF00532: Peripla_BP_1" amino acids 69 to 327 (259 residues), 48.7 bits, see alignment E=1.5e-16 PF13407: Peripla_BP_4" amino acids 69 to 283 (215 residues), 61.1 bits, see alignment E=2.6e-20 PF13377: Peripla_BP_3" amino acids 177 to 339 (163 residues), 94.1 bits, see alignment E=2.1e-30

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 44% identity to zpr:ZPR_2152)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1P7 at UniProt or InterPro

Protein Sequence (344 amino acids)

>Echvi_3914 Transcriptional regulators (Echinicola vietnamensis KMM 6221, DSM 17526)
MQKKKHSIKAIAKELNISVTTVSFVLNGKAEENRISQKLIDKVQAYVKKIGYQPSQLAKS
LRTGKSNIIVFMVEDISNPFFATIAKMIEDQAFKDGYKIIYSSTNNDPAKTMGLISMFRD
LQVDGYILTPPVGMDAGFLSELSRDRNPLILFDRYLPEVDCSYVVIDNYQGAKQGLDLFL
KDGLKKIGFVTIDSDQSQMHERREAYVQMCKKEAIDPKILEIPYDTYSSQETEDAMTAFF
ESNGDLEAVFFATNYLAMKGMQVIKQLGKKIPADLAVIAFDDNEFFKFNTPSVSSIVQPK
EEIARGLIQSMLKLINTPQEERTSHQIVLQASLKERESTQKLTS