Protein Info for Echvi_3910 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Transcriptional regulator/sugar kinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00845, glucokinase [EC: 2.7.1.2] (inferred from 44% identity to psn:Pedsa_3756)Predicted SEED Role
"ROK family member transcriptional repressor"
MetaCyc Pathways
- glycolysis III (from glucose) (10/11 steps found)
- homolactic fermentation (10/12 steps found)
- Bifidobacterium shunt (11/15 steps found)
- sucrose degradation III (sucrose invertase) (3/4 steps found)
- GDP-α-D-glucose biosynthesis (2/3 steps found)
- trehalose degradation IV (2/3 steps found)
- trehalose degradation V (2/3 steps found)
- trehalose degradation I (low osmolarity) (1/2 steps found)
- trehalose degradation II (cytosolic) (1/2 steps found)
- 1,3-propanediol biosynthesis (engineered) (6/9 steps found)
- glucose and glucose-1-phosphate degradation (3/5 steps found)
- heterolactic fermentation (12/18 steps found)
- UDP-N-acetyl-D-galactosamine biosynthesis II (4/7 steps found)
- UDP-N-acetyl-D-glucosamine biosynthesis II (3/6 steps found)
- glycogen degradation II (3/6 steps found)
- chitin biosynthesis (4/9 steps found)
- glycogen degradation I (3/8 steps found)
- sucrose biosynthesis II (3/8 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Galactose metabolism
- Glycolysis / Gluconeogenesis
- Nucleotide sugars metabolism
- Starch and sucrose metabolism
- Streptomycin biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.2
Use Curated BLAST to search for 2.7.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G5K9 at UniProt or InterPro
Protein Sequence (299 amino acids)
>Echvi_3910 Transcriptional regulator/sugar kinase (Echinicola vietnamensis KMM 6221, DSM 17526) MDKNKVVGVDIGGSHITTGLVDIDTNVLDEASLVRREVDSSGSAAAIIEEWKTAIEAIPG YSVQHLKIGIAMPGPFDYPNGISLIEQQGKYTSLYGLEVKKMLAEALGCDETSIHFENDA ACFLQGEVASGAARSFDHAIGLTLGTGLGSSRYHGHFAEDAALWCSPFQGSIVEEFVSTR WFVEAYQKKTGKAITEVRELTLKEENKAYAADIFEEFGENLARFLIDFIQKESPEVIVLG GNITKAEELFLPKVKEELEHAGLSTPIRITELGEQAALIGAACSWKVQKENGSAGSNGQ