Protein Info for Echvi_3908 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: alpha-1,2-mannosidase, putative

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 768 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01180: putative alpha-1,2-mannosidase" amino acids 17 to 762 (746 residues), 657.9 bits, see alignment E=9.3e-202 PF17678: Glyco_hydro_92N" amino acids 26 to 286 (261 residues), 259.9 bits, see alignment E=2.8e-81 PF07971: Glyco_hydro_92" amino acids 293 to 757 (465 residues), 581.4 bits, see alignment E=1.7e-178

Best Hits

KEGG orthology group: None (inferred from 72% identity to zpr:ZPR_2732)

Predicted SEED Role

"Alpha-1,2-mannosidase" in subsystem Mannose Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G487 at UniProt or InterPro

Protein Sequence (768 amino acids)

>Echvi_3908 alpha-1,2-mannosidase, putative (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKILLTSLMGFLAWGTQAQEDLSQYVDPMIGTAKMGHTYPGATVPFGSVQLSPDTDTIP
YEVNGRYNPEVYRYCAGYQYDDATIVGFSHTHFSGTGHSDLGDFLMMPTSGPLQLNPGTE
ADPDSGYRSRFSHDREHAAPAYYQVTLDDYDIDVELTATTRVGVHRYTFAQGEDAHVILD
LMAGIYNYDDKNVWTFMREENDTLVTGFRETTGWARTRKVFFALSFDKPIKQYGNRKYDE
KQAYRGFWGRFNESENFPEIAGRKIRAYFDFDLEDGEQLIAKMAISPVSTAGAIKNMQAE
TPGWDFDAIHQAGVDSWNKELHKVQVKTIQESDKVNFYTAMYHAFLGPTVYGDVDGRYRG
LDMNIHQAEGFTNYTSFSLWDTYRALHPLFNVLQPARNRDMVKSMLAHYDQSVHPMLPIW
SHYANENWCMIGYHSASVIADAVVKETVTADLAHALDAAVTTAQTAYFDGIGAYMEKGYV
PEDVSGASVSKTLEYAYDDWAIAQMADKIGNASISREFAARAENYKNVYDQQTGFMRPKL
KDGSWKQGFDPLDTHGQGFIEGNAWNYSLYVPHAPQEMINMMGGDHRFVEHLDSLFSMDL
PDRYFANTEDISREGIIGNYVHGNEPSHHVVYLYNWTDQAWKSHDKIRMILRAMYQTGAD
GLGGNDDFGQMSAWYLFSALGFYPVAPGSVEYALGSPLVEEATLNLENGKTFTVEAQNQS
EKNQYVSKVLLNGEELHEPFIRHADIMKGGKLTFIMKGRPNKKIFSKD