Protein Info for Echvi_3874 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: aspartate racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 TIGR00035: aspartate racemase" amino acids 28 to 253 (226 residues), 189.3 bits, see alignment E=4e-60 PF01177: Asp_Glu_race" amino acids 34 to 246 (213 residues), 129.5 bits, see alignment E=8.1e-42

Best Hits

Swiss-Prot: 39% identical to YGEA_ECOBD: L-aspartate/glutamate-specific racemase (ygeA) from Escherichia coli (strain B / BL21-DE3)

KEGG orthology group: K01779, aspartate racemase [EC: 5.1.1.13] (inferred from 51% identity to fjo:Fjoh_2497)

Predicted SEED Role

"Aspartate racemase (EC 5.1.1.13)" in subsystem Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 5.1.1.13)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G511 at UniProt or InterPro

Protein Sequence (267 amino acids)

>Echvi_3874 aspartate racemase (Echinicola vietnamensis KMM 6221, DSM 17526)
MPERFGYWEFLIWVRTFFDTKKHEGHDMKKIGIVGGISWTSTLDYYKYINEGINHRLGGL
HAAECVIYSLNFSDIQKVGWVNSFDLIYNACEKLISCHVDAIVLGANTAHLFADEIQAHL
DVPIIHIAEATAKAIKKENLSKVGLLATKFTMEMDFYKDKLLQNNIETIIPAENKDVETI
QYILKNELGKGIVSEASKRKFIRFAEMLVDRGAQGIVLGCTEIPMLIHPSDVGFPVFDTT
KLHVEQIVEYAITGCIPSDESFTSKYE